Successful Treatment of Lipedematous Alopecia using Mycophenolate Mofetil

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Successful treatment of lipedematous alopecia using mycophenolate mofetil.

Lipedematous alopecia (LA) is a rare form of non-scarring alopecia described by Coskey in 1961. To date, 78 cases have been reported in the literature (1). LA generally starts from the vertex, with a centrifuge extension that may affect the whole scalp. Patients may present pain or pruritus along the affected area. Palpation reveals a smooth, diffuse and cotton-wool-like induration (1, 2). Curr...

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Successful treatment of major pemphigus vulgaris relapse with mycophenolate mofetil and high-potent topical corticosteroid

Background: Pemphigus vulgaris (PV) is an autoimmune bullous disorder that is fatal if left untreated. High dose systemic corticosteroids are the basis of therapy. The addition of immunosuppressive agents has improved the disease outcome and reduced the required corticosteroid dose and related toxicity. Mycophenolate mofetil is increasingly used as a steroid-sparing agent in immunotherapy of PV...

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Successful Treatment of Hemophagocytic Lymphohistiocytosis Associated with Lupus Nephritis by Using Mycophenolate Mofetil

An estimated 0.9% to 2.4% of patients with systemic lupus erythematosus (SLE) also have hemophagocytic lymphohistiocytosis (HLH). HLH associated with autoimmune diseases is often refractory to corticosteroid treatment; thus, additional immunosuppressive drugs, such as cyclosporine, cyclophosphamide, or tacrolimus, are required. Here, we describe the case of a 44-year-old Japanese woman who deve...

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Treatment of lupus nephritis by mycophenolate mofetil.

BACKGROUND/AIMS Mycophenolate mofetil (MMF) has been increasingly used for the treatment of lupus nephritis (LN). The aim of this study was to examine the efficacy and safety of MMF used with low doses of corticosteroids as maintenance therapy in patients with LN. METHODS The study covered 35 patients, most of them with proliferative types of LN (5 WHO class III, 26 class IV), while 1 had cla...

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Mycophenolate mofetil treatment in resistant myositis.

OBJECTIVES To assess the efficacy and tolerability of mycophenolate mofetil (MMF) in six patients with myositis refractory to conventional immunosuppressive therapy. METHODS Six patients were identified from hospital notes. All had previously failed to respond to other immunosuppressive treatments. Efficacy was measured as changes in muscle strength, creatine kinase (CK) levels and prednisolo...

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ژورنال

عنوان ژورنال: Acta Dermato Venereologica

سال: 2015

ISSN: 0001-5555

DOI: 10.2340/00015555-2114